Certificate of Analysis
| Product Name: | Nirogacestat dihydrobromide |
| Catalog Number: | M56828 |
| CAS Number: | 1962925-29-6 |
Physical and Chemical Properties
| Formula: | C27H43Br2F2N5O |
| Molecular Weight: | 651.47 |
| Form: | Solid |
| Solubility: | DMSO 80 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Nirogacestat dihydrobromide (PF-3084014 dihydrobromide) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |