Certificate of Analysis
| Product Name: | Nimbolide |
| Catalog Number: | M19347 |
| CAS Number: | 25990-37-8 |
Physical and Chemical Properties
| Formula: | C27H30O7 |
| Molecular Weight: | 466.52 |
| Form: | Solid |
| Solubility: | DMSO 30 mg/mL (ultrasonic and warming) |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |