Certificate of Analysis
| Product Name: | Nilotinib (monohydrochloride monohydrate) |
| Catalog Number: | M5330 |
| CAS Number: | 923288-90-8 |
Physical and Chemical Properties
| Formula: | C28H25ClF3N7O2 |
| Molecular Weight: | 583.99 |
| Solubility: | ≥ 33 mg/mL in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: | .gif) |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Nilotinib (AMN-107) is a Bcr-Abl inhibitor with IC50 less than 30 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |