Certificate of Analysis
| Product Name: | NEO214 |
| Catalog Number: | M59104 |
| CAS Number: | 1361198-80-2 |
Physical and Chemical Properties
| Formula: | C27H35NO5 |
| Molecular Weight: | 453.57 |
| Form: | Oil (density 1.162±0.06 g/mL) |
| Solubility: | DMSO 70 mg/mL |
| Storage: | Pure form -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram and perillyl alcohol. NEO214 has anti-cancer activity and blood-brain barrier (BBB) permeability. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |