Certificate of Analysis

 

Product Name: Mutant IDH1-IN-1
Catalog Number: M14454
CAS Number: 1355326-21-4

Physical and Chemical Properties
Molecular Weight: 498.59
Solubility: DMSO ≥ 45 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Mutant IDH1-IN-1 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.