Certificate of Analysis


Catalog Number: M13852
Product Name: Momelotinib sulfate
CAS Number: 1056636-06-6

Physical and Chemical Properties
Molecular Weight: 610.62
Solubility: DMSO 150 mg/mL, Water 90 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Momelotinib sulfate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.