Certificate of Analysis
| Product Name: | Mofegiline hydrochloride |
| Catalog Number: | M27942 |
| CAS Number: | 120635-25-8 |
Physical and Chemical Properties
| Formula: | C11H14ClF2N |
| Molecular Weight: | 233.69 |
| Form: | Solid |
| Solubility: | DMSO 110 mg/mL (ultrasonic); Water 25 mg/mL (ultrasonic) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Mofegiline hydrochloride (MDL72974A) is an orally active and selective enzyme-activated irreversible inhibitor of MAO-B, with marked selectivity on the MAO-B over MAO-A with IC50s of 3.6 nM (MAO-B) and 680 nM (MAO-A), respectively. Mofegiline hydrochloride is also an inhibitor of semicarbazide-sensitive amine oxidase (SSAO). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |