Certificate of Analysis
| Product Name: | BI-4394 |
| Catalog Number: | M27972 |
| CAS Number: | 1222173-37-6 |
Physical and Chemical Properties
| Formula: | C24H22N4O5 |
| Molecular Weight: | 446.46 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor (IC50=1 nM[1]) for the potential treatment of osteoarthritis. BI-4394 is >1000 selective over other MMPs. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |