Certificate of Analysis
| Product Name: | MM-401 TFA |
| Catalog Number: | M28444 |
| CAS Number: | 1442106-11-7 |
Physical and Chemical Properties
| Formula: | C31H47F3N8O7 |
| Molecular Weight: | 700.75 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |