Certificate of Analysis


Product Name: MLN-4760
Catalog Number: M14300
CAS Number: 305335-31-3

Physical and Chemical Properties
Molecular Weight: 428.31
Solubility: DMSO 90 mg/mL (ultrasonic and adjust pH to 9 with NaOH)
Storage: 2-8°C, dry, sealed
Chemical Structure: MLN-4760 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.