Certificate of Analysis
| Product Name: | ML291 |
| Catalog Number: | M31165 |
| CAS Number: | 1523437-16-2 |
Physical and Chemical Properties
| Formula: | C16H16ClN3O6S |
| Molecular Weight: | 413.83 |
| Form: | Solid |
| Storage: | -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ML291 is a first-in-class, potent chemical probe with an EC50 value of 762 nM that selectively activates the PERK/eIF2a/CHOP (apoptosis) arm of the unfolded protein response (UPR) and induces apoptosis in a variety of solid cancer models for leukemia-related studies. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |