Certificate of Analysis


Catalog Number: M9803
Product Name: MK-8353
CAS Number: 1184173-73-6

Physical and Chemical Properties
Formula: C37H41N9O3S
Molecular Weight: 691.84
Solubility: DMSO ≥ 50 mg/mL
Storage: at -20°C
Chemical Structure: MK-8353 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK1/2 inhibitor, with IC50 values of 23.0 nM and 8.8 nM, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.