Certificate of Analysis


Catalog Number: M1837
Product Name: MK-2206 2HCl
CAS Number: 1032350-13-2

Physical and Chemical Properties
Formula: C25H21N5O.2HCl
Molecular Weight: 480.39
Solubility: DMSO 12 mg/mL
Storage: at -20°C
Chemical Structure: MK-2206 2HCl Structure
Analytical Data
HPLC: Shows Min 100.00% purity
H-NMR: Consistent with structure
Product Information
Description: MK-2206 is a novel allosteric inhibitor of Akt with IC50 values of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.