Certificate of Analysis

 

Product Name: (-)-U-50488 hydrochloride
Catalog Number: M56289
CAS Number: 114528-79-9

Physical and Chemical Properties
Formula: C19H27Cl3N2O
Molecular Weight: 405.79
Form: Solid
Solubility: DMSO ≥ 100 mg/mL; Water 50 mg/mL
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: (-)-U-50488 hydrochloride Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (b>Kd=2.2 nM) over μ-opioid receptor (MOR) (b>Kd=430 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.