Certificate of Analysis
| Product Name: | MI-389 |
| Catalog Number: | M29372 |
| CAS Number: | 2222635-92-7 |
Physical and Chemical Properties
| Formula: | C35H35FN6O6 |
| Molecular Weight: | 654.69 |
| Form: | Solid |
| Solubility: | DMSO 66.67 mg/mL (ultrasonic) |
| Storage: | 4°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |