Certificate of Analysis
| Product Name: | Mc-VC-PAB-SN38 |
| Catalog Number: | M28881 |
| CAS Number: | 1801838-28-7 |
Physical and Chemical Properties
| Formula: | C51H58N8O13 |
| Molecular Weight: | 991.05 |
| Form: | Solid |
| Solubility: | DMSO 28.57 mg/mL (ultrasonic) |
| Storage: | -20°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |