Certificate of Analysis
| Product Name: | LY367385 hydrochloride |
| Catalog Number: | M55228 |
| CAS Number: | 2829282-00-8 |
Physical and Chemical Properties
| Formula: | C10H12ClNO4 |
| Molecular Weight: | 245.66 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL; Water 10 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist, with an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |