Certificate of Analysis
| Product Name: | LY2857785 |
| Catalog Number: | M11248 |
| CAS Number: | 1619903-54-6 |
Physical and Chemical Properties
| Formula: | C26H36N6O |
| Molecular Weight: | 448.6 |
| Solubility: | DMSO ≥ 20 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LY2857785 is a type I reversible ATP-competitive inhibitor of CDK9, CDK8 and CDK7 with IC50 of 11 nM, 16 nM and 246 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |