Certificate of Analysis


Catalog Number: M3535
Product Name: LY2784544 (Gandotinib)
CAS Number: 1229236-86-5

Physical and Chemical Properties
Formula: C23H25ClFN7O
Molecular Weight: 469.94
Solubility: DMSO 54 mg/mL
Storage: at -20°C
Chemical Structure: LY2784544 (Gandotinib) Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: LY2784544 is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.