Certificate of Analysis

 

Product Name: LY-294,002 hydrochloride
Catalog Number: M7901
CAS Number: 934389-88-5

Physical and Chemical Properties
Formula: C19H17NO3 · HCl
Molecular Weight: 343.8
Solubility: DMSO: ≥5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: LY-294,002 hydrochloride Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: LY-294,002 hydrochloride is a potent broad-spectrum PI3K inhibitor with IC50s of 0.5, 0.57, and 0.97 μM for P110α, P110δ, and P110β, respectively; in addition, LY294002 hydrochloride also inhibits CK2, with an IC50 of 98 nM, and can be used in studies related to pancreatic cancer. LY294002 hydrochloride can also inhibit CK2 with an IC50 of 98 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.