Certificate of Analysis
| Product Name: | Ro 6842262 |
| Catalog Number: | M28326 |
| CAS Number: | 1396006-71-5 |
Physical and Chemical Properties
| Formula: | C28H26N4O4 |
| Molecular Weight: | 482.53 |
| Storage: | Store at -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ro 6842262 (LPA1 receptor antagonist 1) is an orally bioavailable, highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM. Ro 6842262 attenuates NHLF human lung fibroblast cell proliferation and contraction in vitro. Ro 6842262 also reduces plasma histamine levels in mouse LPA-challenge model. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |