Certificate of Analysis

 

Product Name: LP117
Catalog Number: M8641
CAS Number: 1056468-55-3

Physical and Chemical Properties
Formula: C21H23ClN4O2S
Molecular Weight: 430.95
Solubility: DMSO: 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: LP117 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: LP117 is a pirinixic acid derivative that interferes with ATP-binding cassette (ABC) transporter ABCB1-mediated substrates transport, including vincristine, vinorelbine, paclitaxel, and actinomycin D, but not doxorubicin, rhodamine 123, or JC-1.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.