Product Name: | Selitrectinib (LOXO-195) |
Catalog Number: | M9107 |
CAS Number: | 2097002-61-2 |
Formula: | C20H21FN6O |
Molecular Weight: | 380.42 |
Solubility: | DMSO ≥ 55 mg/mL (Need ultrasonic) |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
HPLC: | Shows Min 99.67% purity |
H-NMR: | Consistent with structure |
Description: | Selitrectinib (LOXO-195) is a potent and selective, next-generation TRK inhibitor, with IC50 values of 0.6±0.1 nM, <2.5 nM for TRKA and TRKC, respectively. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |