Certificate of Analysis

 

Product Name: Linaclotide
Catalog Number: M7526
CAS Number: 851199-59-2

Physical and Chemical Properties
Formula: C59H79N15O21S6
Molecular Weight: 1526.74
Solubility: DMSO 30 mg/mL; Water 9 mg/mL (adjust pH to 2 with HCl)
Storage: -20°C, dry, sealed
Chemical Structure: Linaclotide Structure
Analytical Data
QC Standard: 99.31%
H-NMR: Consistent with structure
Product Information
Description: Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.