Certificate of Analysis

 

Product Name: Lepunafusp alfa
Catalog Number: M25116
CAS Number: 2396411-71-3

Physical and Chemical Properties
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.