Certificate of Analysis
| Product Name: | Lapachol |
| Catalog Number: | M17443 |
| CAS Number: | 84-79-7 |
Physical and Chemical Properties
| Formula: | C15H14O3 |
| Molecular Weight: | 242.00 |
| Form: | Solid |
| Solubility: | DMSO 66.67 mg/mL |
| Storage: | 4°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Lapachol is a naturally occurring naphthoquinone and orally active, potent inhibitor of dihydroorotic acid dehydrogenase (DHODH).Lapachol has immunosuppressive activity against lymphocytes by inhibiting pyrimidine synthesis through direct blockade of DHODH activity. In addition, Lapachol is a vitamin K antagonist with antitumor and antileishmanial activity that inhibits DNA and RNA synthesis in tumor cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |