Certificate of Analysis
| Product Name: | Lanraplenib succinate |
| Catalog Number: | M49930 |
| CAS Number: | 1800047-00-0 |
Physical and Chemical Properties
| Formula: | C23H25N9O.3/2C4H6O4 |
| Molecular Weight: | 620.64 |
| Form: | Solid |
| Solubility: | DMSO 83.33 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Lanraplenib succinate is a potent, highly selective and orally active splenic tyrosine kinase (SYK) inhibitor and inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor with an IC50 value of 9.5 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |