Certificate of Analysis
| Product Name: | KPT-6566 |
| Catalog Number: | M30801 |
| CAS Number: | 881487-77-0 |
Physical and Chemical Properties
| Formula: | C22H21NO5S2 |
| Molecular Weight: | 443.54 |
| Form: | Solid |
| Solubility: | DMSO 19.23 mg/mL (ultrasonic) |
| Storage: | 4°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | KPT-6566 is a selective and covalent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 value of 640 nM and a Ki value of 625.2 nM for PIN1 PPIase domain. KPT-6566 can be used for the research of cancer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |