Certificate of Analysis

 

Catalog Number: M2608
Product Name: Kobe0065
CAS Number: 436133-68-5

Physical and Chemical Properties
Formula: C15H11ClF3N5O4S
Molecular Weight: 449.79
Solubility: DMSO
Storage: at -20°C
Chemical Structure: Kobe0065 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD, exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.