Certificate of Analysis

 

Product Name: KDM5-C49 hydrochloride
Catalog Number: M31015

Physical and Chemical Properties
Formula: C15H25ClN4O3
Molecular Weight: 344.84
Solubility: DMSO 125 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Analytical Data
QC Standard: ≥99.0%
Product Information
Description: KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases, with IC50s of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C enzymes, respectively. KDM5-C49 hydrochloride can be used for the research of cancer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.