Certificate of Analysis

 

Product Name: K41498 TFA
Catalog Number: M54655
CAS Number: 434938-41-7(free base)

Physical and Chemical Properties
Formula: C162H276N48O46.xC2HF3O2
Molecular Weight: 3632.20 (free base)
Form: Solid
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: K41498 TFA is an antisauvagine-30 (aSvg-30) analog and a strongly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM, and 425 nM for human CRF2α, CRF2β, and CRF1 receptors, respectively.K41498 TFA inhibits sauvagine-stimulated cAMP accumulation in hCRF2α/hCRF2β expressing cells. K41498 TFA can be used in hypotension studies.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.