Certificate of Analysis

 

Product Name: K-7174 dihydrochloride
Catalog Number: M4814
CAS Number: 191089-60-8

Physical and Chemical Properties
Formula: C33H50Cl2N2O6
Molecular Weight: 641.67
Solubility: Water 15 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: K-7174 dihydrochloride Structure
Analytical Data
QC Standard: 100.0%
H-NMR: Consistent with structure
Product Information
Description: K-7174 dihydrochloride is a novel, orally active proteasome and GATA inhibitor, inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.