Certificate of Analysis
| Product Name: | JY-2 |
| Catalog Number: | M42874 |
| CAS Number: | 339103-05-8 |
Physical and Chemical Properties
| Formula: | C13H7Cl2N3O |
| Molecular Weight: | 292.12 |
| Form: | Solid |
| Solubility: | DMSO 90 mg/mL (ultrasonic and warming) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.60% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |