| Description: |
JNJ-55511118 is an AMPA receptor negative regulator containing transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8). 1 It inhibits glutamate-induced calcium flux in HEK293F cells that were cotransfected with TARP-γ8 and GluA1o, GluA1i, GluA2i, GluA3o, or GluA4o (IC50s = 11.22, 12.3, 7.41, 38.02, and 15.85 nM, respectively). |
| Stability and Solubility Advice: |
Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |
