Certificate of Analysis

 

Product Name: JNJ-42226314
Catalog Number: M13413
CAS Number: 1252765-13-1

Physical and Chemical Properties
Formula: C26H24FN5O2S
Molecular Weight: 489.56
Solubility: DMSO ≥ 200 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JNJ-42226314  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: JNJ-42226314 is a competitive, highly selective and reversible inhibitor of non-covalent monoacylglycerol lipase (MAGL). The IC50s of JNJ-42226314 against human Hela cells, human PBMC, mouse brain and rat brain were 1.13 nM, 1.88 nM, 0.67 nM and 0.97 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.