Certificate of Analysis
| Product Name: | JAK2/FLT3-IN-1 |
| Catalog Number: | M49581 |
| CAS Number: | 2387765-27-5 |
Physical and Chemical Properties
| Formula: | C25H34FN7O |
| Molecular Weight: | 467.58 |
| Form: | Solid |
| Solubility: | DMSO 30 mg/mL (ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JAK2/FLT3-IN-1 is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |