Certificate of Analysis

 

Product Name: JAK1-IN-8
Catalog Number: M49577
CAS Number: 1973485-18-5

Physical and Chemical Properties
Formula: C22H23FN4O3S
Molecular Weight: 442.51
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JAK1-IN-8 Structure
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: JAK1-IN-8, a potent JAK1 inhibitor (IC50<500 nM), compound 28, extracted from patent WO2016119700A1.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.