Certificate of Analysis
| Product Name: | JAK-IN-3 |
| Catalog Number: | M28334 |
| CAS Number: | 1400876-94-9 |
Physical and Chemical Properties
| Formula: | C18H20N4O3 |
| Molecular Weight: | 340.38 |
| Form: | Solid |
| Solubility: | DMSO 62.5 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |