Certificate of Analysis

 

Product Name: JAK-IN-27
Catalog Number: M41702
CAS Number: 2673176-36-6

Physical and Chemical Properties
Formula: C20H21F2N7O
Molecular Weight: 413.42
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JAK-IN-27 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: JAK-IN-27 is an orally active and potent JAKS family kinase inhibitor with IC50s of 3.0 nM (TYK2), 7.7 nM (JAK1), 629.6 nM (JAK3), respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.