Certificate of Analysis

 
Product Name: JAK-IN-25
Catalog Number: M41705
CAS Number: 2127110-22-7
Physical and Chemical Properties
Formula: C19H17N5O4
Molecular Weight: 379.37
Form: Solid
Solubility: DMSO 5 mg/mL (ultrasonic and warming)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JAK-IN-25 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: JAK-IN-25 is a potent JAK inhibitor with IC50s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2, JAK1, JAK2, JAK3, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.