Certificate of Analysis
| Product Name: | JAK-IN-1 |
| Catalog Number: | M28195 |
| CAS Number: | 1334673-53-8 |
Physical and Chemical Properties
| Formula: | C20H24N6O2 |
| Molecular Weight: | 380.44 |
| Form: | Solid |
| Solubility: | DMSO 66.67 mg/mL (ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |