Certificate of Analysis
| Product Name: | J-113863 |
| Catalog Number: | M6840 |
| CAS Number: | 353791-85-2 |
Physical and Chemical Properties
| Formula: | C30H37Cl2IN2O2 |
| Molecular Weight: | 655.44 |
| Solubility: | DMSO 45 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | J-113863 is a potent CCR1 chemokine receptor antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |