Certificate of Analysis
| Product Name: | ITI-214 free base |
| Catalog Number: | M21090 |
| CAS Number: | 1160521-50-5 |
Physical and Chemical Properties
| Formula: | C29H26FN7O |
| Molecular Weight: | 507.56 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ITI-214 free base is a potent inhibitor of CNS activity and an orally bioactive PDE1 inhibitor (Ki of 58 pM) with good selectivity for other PDE family members and a range of enzymes, receptors, transporters and ion channels. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |