Certificate of Analysis
| Product Name: | Givinostat hydrochloride monohydrate |
| Catalog Number: | M1730 |
| CAS Number: | 732302-99-7 |
Physical and Chemical Properties
| Formula: | C24H27N3O4.HCl.H2O |
| Molecular Weight: | 475.97 |
| Solubility: | DMSO 75 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.20% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |