Certificate of Analysis
| Product Name: | IDO1/TDO-IN-4 |
| Catalog Number: | M21233 |
| CAS Number: | 461424-21-5 |
Physical and Chemical Properties
| Formula: | C14H10N4 |
| Molecular Weight: | 234.26 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | IDO1/TDO-IN-4 is a potent dual IDO1/TDO inhibitor with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO). IDO1/TDO-IN-4 forms hydrogen bonds with IDO1 and interacts with TDO in π-π stacking. IDO1/TDO-IN-4 can be used in the study of depression, as well as depression-induced infectious, metabolic and autoimmune diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |