Certificate of Analysis

 

Product Name: IDH1 Inhibitor 1
Catalog Number: M54535
CAS Number: 2234285-81-3

Physical and Chemical Properties
Formula: C20H18F4N6O2
Molecular Weight: 450.39
Form: Solid
Solubility: DMSO >100 mg/mL
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: IDH1 Inhibitor 1 Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-permeable, selective mutant IDH1 inhibitor that inhibits IDH1R132H, IDH1R132C, and IDH1WT with IC50s of 0.021 μM, 0.045 μM, and 2.52 μM, respectively. possesses antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.