Certificate of Analysis
| Product Name: | HS38 |
| Catalog Number: | M49488 |
| CAS Number: | 1030203-81-6 |
Physical and Chemical Properties
| Formula: | C14H12ClN5O2S |
| Molecular Weight: | 349.80 |
| Form: | Solid |
| Solubility: | DMSO 7.14 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | HS38 is a potent, selective, ATP-competitive inhibitor of DAPK1 and ZIPK (DAPK3) with Kd values of 300 nM and 280 nM, respectively.In addition, HS38 is an inhibitor of PIM3 with an IC50 value of 200 nM.HS38 has been used in the study of smooth muscle-related diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |