Certificate of Analysis

 

Product Name: HRS-4642
Catalog Number: M58646
CAS Number: 2836263-09-1

Physical and Chemical Properties
Formula: C34H35F3N6O3
Molecular Weight: 632.68
Solubility: DMSO ≥ 65 mg/mL
Storage: Powder -20°C
Chemical Structure: HRS-4642 Structure
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: HRS-4642 is a selective KRAS(G12D) inhibitor, with Kd value of 0.083 nM. HRS-4642 has anti-cancer activity. HRS-4642 exhibits significant in vivo potency.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.