Certificate of Analysis
| Product Name: | HPK1-IN-3 |
| Catalog Number: | M10831 |
Physical and Chemical Properties
| Formula: | C23H22F4N6O2 |
| Molecular Weight: | 490.45 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.5% |
Product Information
| Description: | HPK1-IN-3 is a potent selective ATP competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor,IC50 0.25 nM. HPK1-IN-3 has IL-2 cell potency, EC in human peripheral blood mononuclear cells (PBMCs).50 108 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |