Certificate of Analysis

 

Product Name: HPB
Catalog Number: M8624
CAS Number: 1800066-24-3

Physical and Chemical Properties
Formula: C18H20N2O4
Molecular Weight: 328.36
Solubility: DMSO: 5 mg/mL (warmed)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: HPB Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: HPB is a cell-permeable, non-cytotoxic N-hydroxybenzamide derivative that acts as a HDAC6-selective deacetylase inhibitor (IC50 = 31/376/677/842/1133 nM against HDAC6/8/10/1/7, >2 μM against HDAC2/3/4/11/9/5).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.